Mark W. Bondi, Ph.D., ABPP/CN 

Professor of Psychiatry


Contact Information

VA San Diego Healthcare System (116B)
3350 La Jolla Village Drive
San Diego, CA 92161
T: (858) 552-8585 ext. 2809
F: (858) 642-1218


Dr. Bondi received his doctorate in Clinical Psychology and Neuropsychology from the University of Arizona (1991) and was a National Institutes of Health Postdoctoral Fellow at UCSD from 1991 to 1993. Currently he is a Professor of Psychiatry at UCSD and Director of the Neuropsychological Assessment Unit at the San Diego Veterans Affairs Healthcare System. Dr. Bondi is a licensed psychologist in California and board certified in Clinical Neuropsychology by the American Board of Professional Psychology. He is a Fellow of both the National Academy of Neuropsychology and Division 40 (Clinical Neuropsychology) of the American Psychological Association. He serves on the editorial boards of several prominent journals in neuropsychology and he has published over 150 research articles and book chapters, and he is the co-author of the 2013 book Mild Cognitive Impairment and Dementia: Definitions, Diagnosis and Treatment.

Research Interests

Research Focus

Research focuses on: (1) characterizing the cognitive and brain changes of the preclinical period of Alzheimer’s disease (AD); (2) understanding possible vascular contributions to the development of AD; (3) critically examining the concept of Mild Cognitive Impairment in an effort to improve upon its nosology, clinical characterization and ability to predict clinical outcomes; (4) examining how the profiles of cognitive and brain changes in the development of AD vary by age; (5) developing and refining neuropsychological test measurement strategies in the AD prodrome, (6) examining the effect of disclosing of one’s risk for AD on subjective and objective memory, and (7) examining the role of genetic and neurobehavioral factors in recovery following traumatic brain injury.

Clinical Focus

Dr. Bondi is an active Clinical Neuropsychologist and Co-Director of the Department's private practice plan (UCSD Neuropsychological Associates). He conducts clinical neuropsychological evaluations of adults with a wide range of neurologic and psychiatric disorders. Different test batteries have been developed to respond to specific referral questions arising from diverse patient populations as well as document cognitive changes occurring during the course of disease or treatment. Comprehensive neuropsychological assessments also are requested in the context of medicolegal or disability evaluations.


  • Bondi, M. W., Houston, W. S., Eyler, L. T., & Brown, G. G. (2005). FMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer's disease. Neurology, 64, 501-508.
  • Twamley, E. W., Ropacki, S., & Bondi, M. W. (2006). Neuropsychological and neuroimaging changes in preclinical Alzheimer's disease. Journal of the International Neuropsychological Society, 9, 783-795.
  • Wierenga, C. E., & Bondi, M. W. (2007). Use of functional magnetic resonance imaging in the early identification of Alzheimer's disease. Neuropsychology Review, 17, 127-143.
  • Han, S. D., Houston, W. S., Eyler, L. T., Salmon, D. P., Fleisher, A. S., & Bondi, M. W. (2007). Verbal paired-associate learning by APOE genotype in nondemented older adults: FMRI evidence of a right hemisphere compensatory response. Neurobiology of Aging, 28, 238-247.
  • Han, S. D., Drake, A. I., Cessante, L. M., Jak, A. J., Houston, W. S., Delis, D. C., Filoteo, J. V., & Bondi, M. W. (2007). APOE and TBI in a U.S. military population: Evidence of a neuropsychological compensatory mechanism? Journal of Neurology, Neurosurgery, & Psychiatry, 78, 1103-8.
  • Lineweaver TT, Bondi MW, Galasko D, Salmon DP (2013). Effect of knowledge of APOE genotype on subjective and objective memory performance in healthy older adults. Am J Psychiatry, 171, 201-8.
  • Smith GE, Bondi MW (2013). Mild Cognitive Impairment and Dementia: Definitions, Diagnosis, and Treatment. New York: Oxford University Press.
  • Edmonds EC, Delano-Wood L, Clark LR, Jak AJ, Nation DA, McDonald CR, Libon DJ, Au R, Galasko D, Salmon DP, Bondi MW, for the Alzheimer’s Disease Neuroimaging Initiative (2014). Susceptibility of the conventional criteria for Mild Cognitive Impairment to false positive diagnostic errors. Alzheimers Dement [Epub ahead of print].
  • Bondi MW, Edmonds EC, Jak AJ, Clark LR, Delano-Wood L, McDonald CR, Nation DA, Libon DJ, Au R, Galasko D, Salmon DP, for the Alzheimer’s Disease Neuroimaging Initiative (2014). Neuropsychological criteria for MCI improves diagnostic precision, biomarker associations, and prediction of progression. J Alzheimers Dis, 42, 275-89.