Paul J. Mills, Ph.D. 

Professor In Residence


Contact Information

9500 Gilman Drive
La Jolla, CA 92093-0804
T: (619) 543-2506
F: (619) 543-7517


Dr. Mills has been with the Department since 1987 when he began a postdoctoral fellowship in Behavioral Medicine. He is a long-standing NIH-supported clinical investigator with expertise in psychoneuroimmune processes in human wellness and disease with over 300 manuscripts and book chapters on these topics. His research interests include examining the effects of complementary and alternative medicine treatments for fatigue, pain, physical functioning and PTSD. He is a former president of the American Psychosomatic Society, former Associate Editor of the journals Health Psychology, Annals of Behavioral Medicine, and Journal of the Society for Integrative Oncology, and former Guest Editor of the journal Annals of Behavioral Medicine. He is currently on the Editorial Board of the journal Brain, Behavior and Immunity and an Associate Editor for the textbook Behavioral and Social Science in Medicine: Principles and Practice of Biopsychosocial Care (S. Waldstein, Ed.) (Springer). He is an active faculty member in the Behavioral Medicine track of the SDSU/UCSD Joint Doctoral Program in Clinical Psychology and the Health Behavior track of the SDSU/UCSD Joint Doctoral Program in Public Health. He is Director of the Clinical Research Biomarker Laboratory at UCSD, Co-Director of the Translational Research Technologies Division at the UCSD Clinical Translational Research Institute, and Director of Collaborative Research Program Development at the UCSD Center of Integrative Medicine.

Research Interests

Not available at this time.


  • Mills PJ , Kennedy BP, Loredo J, Dimsdale JE, & , Ziegler MG. Effects of Nasal Continuous Positive Airway Pressure and Oxygen on Norepinephrine Kinetics and Cardiovascular Responses in Obstructive Sleep Apnea. Journal of Applied Physiology 100(1):343-348, 2006.
  • Mills PJ, Hong S, Redwine L, Carter SM, Chiu A, Ziegler MG, Dimsdale JE, Maisel AS. Physical fitness attenuates leukocyte - endothelial adhesion in response to acute exercise. Journal of Applied Physiology 101(3):785-788, 2006.
  • Malarkey WB, Mills PJ. Invited Review, Named Series: Twenty Years of Brain Behavior & Immunity Endocrinology: The Active Partner in PNI research. Brain, Behavior & Immunity 21:161-168, 2007.
  • Edwards KM, Ziegler MG, Mills PJ. The potential anti-inflammatory benefits of improving physical fitness in hypertension. Journal of Hypertension 25(8):1533-1542, 2007.
  • Mills PJ, Shapiro D, Goldstein IB, Ottaviani C, Pung MA, Khandrika S, von Känel R, Rutledge TR. Metabolic Predictors of Inflammation, Adhesion, and Coagulability in Healthy Younger Aged Adults. Obesity 16:2702-2706, 2008.
  • Wirtz PH, Hong S, Redwine LS, Tafur J, Rutledge T, Ziegler MG, Greenberg BH, Mills PJ. Depressive symptoms are associated with soluble P-selectin (sP-selectin) reactivity to acute exercise in heart failure. Biological Psychiatry 65:801-807, 2009.
  • Mills PJ, Natarajan L, von Känel R, Ancoli-Israel S, Dimsdale JE. Diurnal Variability of C-reactive Protein in Obstructive Sleep Apnea. Sleep and Breathing 13:415-420, 2009.
  • Mills PJ, Dimsdale JE, Natarajan L, Ziegler MG, Maisel A, Greenberg BH. Sleep and Health-Related Quality of Life in Heart Failure. Congestive Heart Failure 15:228-233, 2009.
  • Jain S, Mills PJ. Biofield Therapies: helpful or full of hype? A best-evidence synthesis. International Journal of Behavioral Medicine 17:1-16, 2010.
  • Tafur J, Van Wijk EPA, Van Wijk R, Mills PJ. Biophoton Detection and Low-Intensity Light Therapy: A Potential Clinical Partnership. Photomedicine and Laser Surgery 28:23-30, 2010.
  • Redwine LS, Wirtz PH, Hong S, Ziegler MG, Greenberg BH, Mills PJ. Norepinephrine secretion and lymphocyte catecholamine-induced chemotaxis following exercise in heart failure patients and controls: associations with depressive symptoms. Journal of the American College of Cardiology, in press.