Erick Tatro, Ph.D.
Assistant Professor
Email: etatro@ucsd.edu
Phone #: 858-232-9778
FAX #: 858-534-4484
Biography
Dr. Tatro received his B.S. from The Ohio State University double majoring in Chemistry and Biology. He received his Ph.D. from University of Pittsburgh School of Medicine in Molecular and Cellular Pathology, studying the role of immunophilins in hormone trafficking in neurons. During graduate study, he completd a minor project in Cellular Approaches to Tissue Engineering and Regeneration with the McGowan Institute for Regenerative Medicine at University of Pittsburgh. After a post-doctoral study at UCSD Department of Psychiatry, Dr Tatro became Assistant Professor in 2010.
Research Focus
Dr. Tatro's research is in the broad area of molecular and cellular neuroscience. Specifically, his projects are focusing on HIV - induced cytokine and chemokine signaling to neurons, methamphetamine - induced changes in microRNA repertoire, and microRNA and gene regulation in the central nervous system as it pertains to HIV and comorbid influences. His research employs a broad array of methodologies, including neuronal and microglia cell culture, 3-D and high-power cellular imaging and microscopy, clinical studies of biological correlates to neuropsychiatric parameters.
In addition, Dr. Tatro is interested in clinical studies involving molecular basis for successful cognitive aging, methamphetamine and addiction biology, and HIV- associated neurocognitive deficit.
Selected Publications
- Tatro ET, Everall IP, Masliah E, Hult BJ, Lucero G, Chana G, Soontornniyomkij V, Achim CL; HIV Neurobehavioral Research Center. “Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder.” Journal of Neuroimmune Pharmacology. 4(2):218-26. June, 2009. Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929573
- Glatt, SJ: Chandler, SD;* Bousman, CA;* Chana, G; Lucero GR, Tatro, ET; May, T; Lohr, JB; Kremen, WS; Everall, IP; and Tsuang, MT. “Alternatively Spliced Genes as Biomarkers for Schizophrenia, Bipolar Disorder and Psychosis: A Blood-Based Spliceome-Profiling Exploratory Study.” (*Contributed equally to this work). Current Pharmacogenomics and Personalized Medicine. June 2009.
- Tatro ET, Everall IP, Kaul M, Achim CL. “Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: Implications for major depressive disorder.” Brain Research. August 25, 2009.1286: 1-12. Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724600/
- Tatro ET, Scott ER, Nguyen TB, Salaria S, Banjeree S, Moore D, Masliah E, Achim C, and Everall IP. (2010) “Evidence for Alteration of Gene Regulatory Networks through MicroRNA's of the HIV-Infected Brain: Novel Analysis of Retrospective Cases” PLoSONE. 5(4): e10337. Link: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010337
- Tatro ET, Nguyen TB, Bousman CA, Masliah E, Grant I, Atkinson HJ, Everall IP. “Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in HIV-infected individuals” Journal of Neurovirology. Link: www.pubmed.gov/20726698
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