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ONEMIND Publications

Highlighted Papers

Key Publications

  • Garland, E.L., Hudak, J., Hanley, A.W., Bernat, E., & Froeliger, B. (2025). Positive emotion dysregulation in opioid use disorder and normalization by Mindfulness-Oriented Recovery Enhancement. JAMA Psychiatry, 82(7), p. 654-662. https://pmc.ncbi.nlm.nih.gov/articles/PMC12044540/
  • Garland, E.L. (2025). Recovering wellbeing from the diseases of despair: Integrating neuroscience, evidence-based practice, and policy to heal the opioid crisis. Nature Mental Health. https://doi.org/10.1038/s44220-024-00378-z
  • Lewis, B.R., Hendrick, J., Byrne, K., Odette, M., Wu, C., & Garland, E.L. (2025). Psilocybin-assisted group psychotherapy and Mindfulness-Based Stress Reduction (MBSR) for frontline healthcare provider COVID-19 related depression and burnout: A randomized clinical trial. PLOS Medicine. https://pubmed.ncbi.nlm.nih.gov/39802794/
  • Gullapalli, B., Lao, Y., Rahman, T., Garland, E.L. (2025). Opioid misuse detection from cognitive and physiological data with temporal fusion deep learning. Drug and Alcohol Dependence https://pubmed.ncbi.nlm.nih.gov/40684523/
  • Zgierska, A.E., Edwards, R.R., Barrett, B., Burzinski, C.A., Jamison, R.N., Nakamura, Y., Henningfield, M.F., Tuan, W., Shen, C., Sehgal, N., Lennon, R.P., Dong, H., Chinchilli, V.M., Liu, Y., Turnquist, A., Schiefelbeing, A.R., Jacob, E.A., Vesaley, C., Cowan, P., Garland. E.L. (2025). Mindfulness versus cognitive behavioral therapy for chronic low back pain treated with opioids: Comparative effectiveness randomized clinical trial. JAMA Network Open. https://pmc.ncbi.nlm.nih.gov/articles/PMC11976494/
  • Sacchet, M.D., Fava, M., & Garland, E.L. (2024). Modulating self-referential processing through meditation and psychedelics: is scientific investigation of self-transcendence clinically relevant? World Psychiatry, 23(2), 298-299. https://pmc.ncbi.nlm.nih.gov/articles/PMC11083968/
  • Garland, E. L., Nakamura, Y., Bryan, C. J., Hanley, A. W., Parisi, A., Froeliger, B., Marchand, W. R., & Donaldson, G. W. (2024). Mindfulness-Oriented Recovery Enhancement for Veterans and Military Personnel on Long-Term Opioid Therapy for Chronic Pain: A Randomized Clinical Trial. The American Journal of Psychiatry, 181(2), 125–134. https://doi.org/10.1176/appi.ajp.20230272
  • Cooperman, N. A., Lu, S.-E., Hanley, A. W., Puvananayagam, T., Dooley-Budsock, P., Kline, A., & Garland, E. L. (2024). Telehealth Mindfulness-Oriented Recovery Enhancement vs Usual Care in Individuals With Opioid Use Disorder and Pain: A Randomized Clinical Trial. JAMA Psychiatry, 81(4), 338–346. https://doi.org/10.1001/jamapsychiatry.2023.5138
  • Garland, E. L., Recasens, M., Taple, B. J., Donaldson, G. W., & Weisberg, R. B. (2024). Virtual reality-based Mindfulness-Oriented Recovery Enhancement (MORE-VR) as an adjunct to medications for opioid use disorder: a Phase 1 trial. Annals of Medicine, 56(1), 2392870. https://doi.org/10.1080/07853890.2024.2392870
  • Parisi, A., Hudak  J., Froeliger, B., & Garland, E.L. (2023). Mindfulness-Oriented Recovery Enhancement reduces posttraumatic stress by enhancing reappraisal among chronic pain patients with co-occurring opioid misuse. Nature Mental Health, 1, 489- 500. https://pmc.ncbi.nlm.nih.gov/articles/PMC6764586/
  • Garland, E. L., Fix, S. T., Hudak, J. P., Bernat, E. M., Nakamura, Y., Hanley, A. W., Donaldson, G. W., Marchand, W. R., & Froeliger, B. (2023). Mindfulness-Oriented Recovery Enhancement remediates anhedonia in chronic opioid use by enhancing neurophysiological responses during savoring of natural rewards. Psychological Medicine, 53(5), 2085–2094. https://doi.org/10.1017/S0033291721003834
  • Garland, E. L., Gullapalli, B. T., Prince, K. C., Hanley, A. W., Sanyer, M., Tuomenoksa, M., & Rahman, T. (2023). Zoom-Based Mindfulness-Oriented Recovery Enhancement Plus Just-in-Time Mindfulness Practice Triggered by Wearable Sensors for Opioid Craving and Chronic Pain. Mindfulness, 14(6), 1329–1345. https://doi.org/10.1007/s12671-023-02137-0
  • Garland, E. L., Roberts, R. L., Hanley, A. W., Zeidan, F., & Keefe, F. J. (2023). The Mindful Reappraisal of Pain Scale (MRPS): Validation of a New Measure of Psychological Mechanisms of Mindfulness-Based Analgesia. Mindfulness, 14(1), 192–204. https://doi.org/10.1007/s12671-022-02034-y
  • Garland, E.L., Hanley, A.W., Hudak, J., Nakamura, Y., Froeliger, B. (2022). Mindfulness-induced endogenous theta stimulation occasions self-transcendence and inhibits addictive behavior. Science Advances, 8(41), eabo4455. https://pubmed.ncbi.nlm.nih.gov/36223472/ 
  • Hudak, J., Bernat, E.M., Fix, S.T., Prince, K.C., Froeliger, B., & Garland, E.L. (2022). Neurophysiological deficits during reappraisal of negative emotional stimuli in opioid misuse. Biological Psychiatry, 12(15), 1070-1078. https://pubmed.ncbi.nlm.nih.gov/35393080/ 
  • Parisi, A., Roberts, R. L., Hanley, A. W., & Garland, E. L. (2022). Mindfulness-Oriented Recovery Enhancement for Addictive Behavior, Psychiatric Distress, and Chronic Pain: A Multilevel Meta-Analysis of Randomized Controlled Trials. Mindfulness, 13(10), 2396–2412. https://doi.org/10.1007/s12671-022-01964-x
  • Garland, E. L., Hanley, A. W., Nakamura, Y., Barrett, J. W., Baker, A. K., Reese, S. E., Riquino, M. R., Froeliger, B., & Donaldson, G. W. (2022). Mindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical Trial. Archives of Internal Medicine, 182(4), 407–417. https://doi.org/10.1001/jamainternmed.2022.0033
  • Garland, E.L. (2021). Mindful positive emotion regulation as a treatment for addiction: From hedonic pleasure to self-transcendent meaning. Current Opinion in Behavioral Sciences, 39, 168-177. https://pmc.ncbi.nlm.nih.gov/articles/PMC8168946/ 
  • Hudak, J., Hanley, A.W., Marchand, W.R., Nakamura, Y., Yabko, B., Garland, E.L. (2021). Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with Mindfulness-Oriented Recovery Enhancement. Neuropsychopharmacology, 46(4), 836–843. https://pubmed.ncbi.nlm.nih.gov/32919401/
  • Garland, E.L., Brintz, C.E., Hanley, A.W., Roseen, E.J., Atchley, R.M., Gaylord, S.A., Faurot, K., Yaffe, J., Fiander, M., Keefe, F.J. (2020). Mind-body therapies for opioid-treated pain: A systematic review and meta-analysis of mental techniques to improve clinical pain and opioid-related outcomes. JAMA Internal Medicine, 180(1), 91-105. https://pubmed.ncbi.nlm.nih.gov/31682676/
  • Garland, E.L., Atchley, R.M., Hanley, A.W., Zubieta, J.K., & Froeliger, B. (2019). Mindfulness-Oriented Recovery Enhancement remediates hedonic dysregulation in opioid users: Neural and affective evidence of target engagement. Science Advances, 5(10), eaax1569. https://pmc.ncbi.nlm.nih.gov/articles/PMC6795512/ 
  • Garland, E. L., & Howard, M. O. (2018). Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research. Addiction Science & Clinical Practice, 13(1), 14. https://doi.org/10.1186/s13722-018-0115-3
  • Li, W., Howard, M. O., Garland, E. L., McGovern, P., & Lazar, M. (2017). Mindfulness treatment for substance misuse: A systematic review and meta-analysis. Journal of Substance Abuse Treatment, 75, 62–96. https://doi.org/10.1016/j.jsat.2017.01.008
  • Garland, E. L., Gaylord, S. A., & Fredrickson, B. L. (2011). Positive Reappraisal Mediates the Stress-Reductive Effects of Mindfulness: An Upward Spiral Process. Mindfulness, 2(1), 59–67. https://doi.org/10.1007/s12671-011-0043-8
  • Garland, E. L., Fredrickson, B., Kring, A. M., Johnson, D. P., Meyer, P. S., & Penn, D. L. (2010). Upward spirals of positive emotions counter downward spirals of negativity: Insights from the broaden-and-build theory and affective neuroscience on the treatment of emotion dysfunctions and deficits in psychopathology. Clinical Psychology Review, 30(7), 849–864. https://doi.org/10.1016/j.cpr.2010.03.002